Life's essential 8 and longevity: the sustained impact of cardiovascular health on mortality from middle age to centenarians - PubMed
3 hours ago
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- #longevity
- #cardiovascular health
- Higher cardiovascular health scores (Life's Essential 8) are linked to reduced mortality risk across all adult life stages, including centenarians.
- Centenarians with high cardiovascular health have a 54.8% lower mortality risk, with physical activity and body mass being key factors.
- A near-linear dose-response relationship exists between cardiovascular health scores and mortality reduction, with population-attributable fractions reaching 36.8% in centenarians.
- The findings challenge therapeutic nihilism in the oldest-old and highlight the need for age-specific strategies to extend healthy lifespan.