Migraine in women undergoing fertility treatment: A prospective study - PubMed
2 hours ago
- #women's health
- #migraine
- #in vitro fertilization
- The study assessed migraine burden and disability in women with and without migraine during an IVF cycle, finding that women with migraine consistently had higher headache-related disability (measured by HALT-30 scores) at all time points compared to controls.
- No significant increase in headache-related disability was observed over time during the IVF cycle for women with migraine, including between peak and nadir estradiol levels after ovulation trigger, suggesting hormonal shifts may not exacerbate migraine disability beyond baseline.
- Women with migraine reported greater psychological distress (stress, anxiety, and depression) than controls throughout the study, highlighting the need for mental health support during IVF treatment.
- The study included 76 participants (52 with migraine, 24 controls) and collected data on headache disability, psychological symptoms, and hormone levels at three time points in an IVF cycle.
- Findings indicate that migraine disability may not increase during IVF treatment, but the study could not rule out transient exacerbations not captured by the HALT-30 measure.