Natural Bioactive Compounds in Polycystic Ovary Syndrome: Properties, Molecular Mechanisms, and Therapeutic Potential - PubMed
3 hours ago
- #PCOS
- #metabolic-endocrine disorder
- #natural bioactive compounds
- PCOS is a common metabolic-endocrine disorder in women of reproductive age, characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology.
- The syndrome is often associated with hyperinsulinemia, obesity, dyslipidemia, chronic inflammation, and increased risks of type 2 diabetes and cardiovascular disease.
- Conventional treatments like oral contraceptives and metformin have limitations in efficacy, tolerability, and addressing underlying metabolic issues.
- Natural bioactive compounds from phytochemicals show promise as complementary therapies, offering antioxidant, anti-inflammatory, and hypoglycemic effects.
- These compounds target molecular pathways involved in insulin resistance, hyperandrogenism, and follicular dysfunction, potentially improving metabolic, hormonal, and reproductive outcomes in PCOS.