Halofantrine protects photoreceptors in multiple models of retinal degeneration - PubMed
3 hours ago
- #photoreceptor protection
- #retinal degeneration
- #halofantrine
- Halofantrine shows strong protection of rod and cone photoreceptors across multiple inherited retinal degeneration models.
- The protective effect is independent of gene mutations and involves upregulation of oxidative phosphorylation and ribosomal processes.
- Subconjunctival injection improves retinal function despite transient exposure, suggesting potential for ocular delivery like eye drops.