Air Pollution Elevates Risks of Incident Hypertension, Subsequent Comorbidities Progression and Prognosis: A Multistate Analysis - PubMed
3 days ago
- #Hypertension
- #Air pollution
- #Comorbidity progression
- Long-term exposure to air pollutants (PM2.5, NO2, NOx) increases risk of developing hypertension and progressing to comorbidities and death.
- PM2.5, NO2, and NOx each elevate risk across hypertension progression stages, with hazard ratios ranging from 1.03-1.09, 1.07-1.19, and 1.05-1.10.
- Air pollution accelerates progression to cardiovascular and renal comorbidities like ischemic heart disease, atherosclerosis, and chronic kidney disease.
- Body mass index and lung function mediate 7.7%-25.3% of the associations between nitrogen oxides and hypertension onset/comorbidity progression.