Efficacy and Safety of Fimasartan/Indapamide Combination Therapy versus Fimasartan Monotherapy in Patients with Essential Hypertension Inadequately Responding to Fimasartan 30 mg (FINEDUO): A Randomiz
3 hours ago
- #hypertension
- #combination therapy
- #clinical trial
- The FINEDUO study compared fimasartan/indapamide SR combination therapy with fimasartan monotherapy in hypertensive patients inadequately controlled on fimasartan 30 mg.
- Combination therapy showed significantly greater reductions in systolic and diastolic blood pressure at weeks 4 and 8 compared to monotherapy.
- Blood pressure control and response rates were higher with combination therapy, while safety profiles were similar between groups, including in elderly patients.
- The study concluded that fimasartan/indapamide SR is a superior, rapid, and safe option for hypertension management, especially in high-risk or older adults.