Deconstructing White Dot Syndromes - Multimodal Imaging in Uveitis (MUV) Taskforce: Report 11 - PubMed
5 hours ago
- #Multimodal Imaging
- #White Dot Syndromes
- #Uveitis
- The term 'white dot syndromes' (WDS) historically groups non-infectious posterior uveitis entities based on similar funduscopic appearances, but its relevance is questioned in the era of advanced imaging.
- Multimodal imaging (OCT, OCTA, ICGA) reveals profound differences among six classic WDS entities, each with distinct anatomic features and patterns of tissue involvement.
- Imaging-based hypotheses suggest different immunopathogenic pathways for each entity, indicating WDS as a classification does not account for major biological and prognostic differences.
- A paradigm shift toward disease-specific terminology is recommended to improve diagnostic precision, guide management, and reflect pathophysiological diversity.