Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta-Analysis - PubMed
3 hours ago
- #Periodontal Treatment
- #Gingival Enlargement
- #Risk Factors
- Poor oral hygiene is consistently identified as a major risk factor for gingival enlargement (GE), particularly in drug-influenced cases.
- Drug-induced gingival enlargement (DIGE) is significantly associated with medications like phenytoin, calcium-channel blockers (CCBs), and cyclosporine A (CsA), with patients on CCBs having higher DIGE risk than those on other antihypertensives, and CsA users more than tacrolimus users.
- Effective management strategies include oral hygiene instructions (OHIs) and professional mechanical plaque removal (PMPR) as foundational treatments, supplemented by adjuncts like systemic azithromycin or medication change, especially in severe or recurrent cases.