Association of probiotic medication use with incident Parkinson disease and alzheimer disease: a nationwide nested case-control study - PubMed
5 hours ago
- #Neurodegenerative Diseases
- #Case-Control Study
- #Probiotics
- Study investigated probiotic medication use and its association with incident Parkinson's disease and Alzheimer's disease.
- Used a nationwide Japanese claims database from 2005-2025 for a nested case-control analysis.
- Found probiotic use was associated with a 44% lower risk of neurodegenerative diseases overall (OR 0.56).
- Specifically reduced risk for Parkinson's disease (OR 0.54) and Alzheimer's disease (OR 0.63).
- Supports the role of intestinal environment in neurodegeneration and warrants further prospective research.