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Life's Essential 8, genetic susceptibility, and risk of cognitive impairment: results from an elder population-based cohort study - PubMed

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  • #cognitive impairment
  • #genetic susceptibility
  • #Life's Essential 8
  • High Life's Essential 8 (LE8) scores are linked to lower cognitive impairment in older Chinese adults, with a prevalence ratio of 0.65.
  • A joint association exists between LE8 and genetic risk, where low LE8 scores combined with high genetic risk show the highest prevalence ratio of 1.19.
  • Optimal cardiovascular health may help reduce cognitive impairment and mitigate genetic risks in the elderly population in western China.