Impact of Biologic Treatment Duration on Drug-Free Remission in Moderate-to-Severe Psoriasis: A Retrospective Cohort Study - PubMed
2 hours ago
- #Treatment Duration
- #Biologics
- #Psoriasis
- Long-term biologic treatment (4-6 years) leads to longer drug-free remission compared to short-term treatment (≤2.5 years) in moderate-to-severe psoriasis patients.
- Interleukin-23 inhibitors like risankizumab show a significant reduction in relapse risk with long-term therapy, suggesting a potential disease-modifying effect.
- Anti-IL-17 inhibitors like secukinumab did not show significant differences in drug-free remission between short-term and long-term treatment groups.
- The study is retrospective and preliminary, requiring confirmation through larger prospective studies.