Histone H3 lysine 18 lactylation-mediated SULF1 transcription promotes atherosclerosis by regulating endothelial-to-mesenchymal transition - PubMed
3 hours ago
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- #SULF1
- #EndMT
- SULF1 plays a critical role in EndMT and atherosclerosis.
- Oxidative stress increases SULF1 expression, promoting EndMT via the WNT/SLUG pathway.
- Histone H3 lysine 18 lactylation, regulated by HDAC3, activates SULF1 transcription.