Targeting EpCAM expression via near-infrared fluorescent antibodies enables microscopic delineation of primary and recurrent HNSCC - PubMed
3 hours ago
- #HNSCC delineation
- #EpCAM-targeted imaging
- #Fluorescence-guided surgery
- Targeting EpCAM with near-infrared fluorescent antibodies aids in distinguishing primary and recurrent HNSCC tissue from non-malignant areas.
- High and consistent EpCAM expression was confirmed in patient samples, with fluorescence intensity significantly higher in HNSCC compared to surrounding tissues.
- IRDye800CW-labeled anti-EpCAM antibodies enable microscopic delineation, potentially improving precision in fluorescence-guided surgery for tumor resection.