Admission blood pressure percentiles and in-hospital mortality in pediatric heart failure: a multicenter retrospective cohort study - PubMed
2 days ago
- #pediatric heart failure
- #blood pressure percentiles
- #in-hospital mortality
- Systolic blood pressure (SBP) percentiles have a U-shaped association with in-hospital mortality in pediatric heart failure, with lowest risk at the 63.8th percentile and increased risk below the 57th and above the 91st percentiles.
- Diastolic blood pressure (DBP) percentiles show a linear inverse association with mortality, with risk increasing below the 83rd percentile.
- Sex-stratified analyses indicate girls are more vulnerable to high SBP (≥91st percentile), while boys are more susceptible to low DBP (<83rd percentile).
- The established BP percentile thresholds for mortality risk stratification are SBP between the 57th-91st percentiles and DBP between the 83rd-100th percentiles.
- The study includes 2545 children across 30 Chinese centers from 2013-2022, using restricted cubic splines and machine learning for analysis.