Endophthalmitis caused by gram-negative bacteria: etiologies, antibiotic susceptibilities, and treatment outcomes - PubMed
3 hours ago
- #Antibiotic susceptibility
- #Gram-negative endophthalmitis
- #Treatment outcomes
- Most common Gram-negative bacteria causing endophthalmitis were Pseudomonas aeruginosa (41.3%), Haemophilus influenzae (17.4%), and others like Klebsiella pneumoniae, Morganella morganii, and Serratia marcescens.
- Primary etiologies included post-operative cases (43.5%), followed by bleb-associated, corneal ulcer, trauma, endogenous, and suture-related infections.
- High antibiotic susceptibility rates were observed for amikacin (94.1%), gentamicin (91.7%), ceftazidime (97.3%), tobramycin (94.3%), ciprofloxacin (91.9%), and meropenem (100%), with lower rates for trimethoprim-sulfamethoxazole (66.7%) and ceftriaxone (86.7%).
- Visual outcomes were poor, with only 13% of patients achieving visual acuity of 20/800 or better, 30.4% having no light perception, and 28.3% requiring enucleation or evisceration despite treatment.