Altered brain glucose metabolism and connectivity in young adults with obstructive sleep apnea - PubMed
3 hours ago
- #sleep apnea
- #brain metabolism
- #neurodegeneration
- Young adults with moderate-to-severe obstructive sleep apnea (OSAS) show altered brain glucose metabolism, including fronto-parietal hypometabolism and cerebellar hypermetabolism.
- Cerebellar glucose hypermetabolism is linked to reduced rapid eye movement (REM) sleep latency and duration.
- Seed-based connectivity analysis indicates disruptions in attentional and limbic networks in patients with OSAS.
- Early diagnosis and treatment of moderate-to-severe OSAS may help prevent worsening brain damage and potential neurodegenerative processes.
- The study suggests OSAS may be a causal factor in brain dysfunction, independent of systemic or neurological comorbidities.