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Gabapentin and Pregabalin Overdoses and Their Management: An Update - PubMed

an hour ago
  • #overdose management
  • #gabapentinoids
  • #pain management
  • Gabapentinoids, including gabapentin and pregabalin, are increasingly prescribed for conditions like neuropathic pain and fibromyalgia.
  • Overdoses involving these drugs are often linked to concurrent use with other substances, particularly opioids, and can be lethal.
  • While effective in reducing opioid prescriptions, gabapentinoids pose risks, especially in high-risk groups such as those with organ failure or comorbidities.
  • Guidelines and decision-making tools should address the balance of benefits and risks compared to opioids and other pain management alternatives.
  • Prescribers must monitor for misuse or abuse and exercise caution when prescribing to special populations.