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A breakthrough in electron microscopy delivers sharper images of body's proteins

5 hours ago
  • #electron-microscopy
  • #biotechnology
  • #protein-imaging
  • Phase contrast technique adapted to electron microscopes improves imaging of small proteins.
  • Laser phase plate enhances cryoelectron microscopy and tomography, enabling clearer views of cellular structures.
  • Technology allows visualization of proteins as small as 17 kilodaltons, covering most of the human proteome.
  • Collaboration between UC Berkeley and Biohub leads to advanced microscopes like Theia with dual-laser systems.
  • Breakthrough expected to revolutionize understanding of molecular functions in cellular contexts.