PET-guided early identification of CAR-T candidates in diffuse large b-cell lymphoma: a multidisciplinary expert consensus - PubMed
3 hours ago
- #DLBCL
- #CAR-T therapy
- #PET/CT
- PET/CT provides prognostic data throughout DLBCL disease course, with baseline metrics like metabolic tumor volume improving risk stratification.
- Interim PET using Deauville score and SUVmax changes enables early identification of high-risk or refractory patients for timely CAR-T referral.
- Standardization of PET/CT acquisition and reporting is crucial for reproducibility and clinical integration to optimize outcomes.