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The Therapeutic Effects of Dietary Supplements on OCD: A Narrative Review - PubMed

4 hours ago
  • #Biomarkers
  • #Nutritional Supplements
  • #OCD Treatment
  • Sufficient nutrients are important in obsessive-compulsive disorder (OCD) pathophysiology, with many studies examining symptom alleviation through nutritional changes.
  • This review synthesized knowledge on serum nutrient levels and nutraceuticals, including vitamins, minerals, amino acids, and supplements like N-acetylcysteine and omega-3.
  • Notable differences in homocysteine, glutamate, vitamin B₁₂, vitamin E, and zinc were observed between OCD individuals and healthy controls, suggesting potential biomarkers and therapeutic targets.
  • Supplementation with vitamin C, B vitamins, vitamin E, zinc, and N-acetylcysteine may contribute to OCD symptom improvement based on preliminary evidence.
  • Nutritional interventions appear to offer safe adjunctive benefits in OCD treatment through anti-inflammatory and antioxidant pathways, but further research is needed due to study heterogeneity and small sample sizes.