mRNA vaccine targeting tick proteins induces tick resistance in guinea pigs22 days agohttps://medicine.yale.edu/news-article/yale-researchers-advance-work-in-diagnosi...IscREAM是一种强大的工具，可同时将免疫应答映射到许多蜱虫蛋白上。测试了52份患者血清；其中33份平均识别出8种抗原，总计识别了177种抗原。将据报道具有抗性的患者血清转移给豚鼠后，证实了蜱虫抗性。用编码25种蜱虫胶合抗原的mRNA疫苗免疫豚鼠，结果显示豚鼠产生了抗性。更多...