The Prevalence of Frailty and Its Non-Linear Associations With Depressive Symptoms Among Cancer Survivors: A Multicenter Study With Network Analyses - PubMed
2 hours ago
- #Frailty
- #Depressive Symptoms
- #Cancer Survivors
- Prevalence of pre-frailty was 35.7% and frailty was 12.7% among hospitalized cancer survivors.
- Each 1-point increase in PHQ-9 score raised odds of pre-frailty and frailty, with non-linear patterns showing steeper increases below specific PHQ-9 thresholds.
- Network analysis identified fatigue, poor appetite, and psychomotor changes as the depressive symptoms most strongly linked to frailty.
- The study suggests routine screening for frailty and depressive symptoms, emphasizing the role of somatic symptoms.