Impact of fluoxetine on innate immunity and melanoma metastasis in mice - PubMed
5 hours ago
- #immunity
- #fluoxetine
- #melanoma
- Fluoxetine, a selective serotonin reuptake inhibitor, was studied for its effects on melanoma metastasis and innate immunity in mice.
- Administering fluoxetine after tumor cell injection reduced lung metastases, decreased immobility time in forced swimming tests, and increased splenocyte activity.
- Fluoxetine given before tumor cell injection had the opposite effect, accelerating cancer progression and negatively impacting immunity.
- The study highlights the timing of fluoxetine administration as critical for its effects on melanoma growth and immune response.