Shape-sensing robotic-assisted bronchoscopy with integrated mobile cone-beam CT for small nodules: results from the prospective multicentre CONFIRM study - PubMed
4 days ago
- #Lung Cancer
- #Cone-beam CT
- #Bronchoscopy
- Shape-sensing robotic-assisted bronchoscopy (ssRAB) integrated with mobile cone-beam CT (mCBCT) was studied for small peripheral pulmonary nodules (PPNs).
- The prospective multicentre CONFIRM study enrolled 155 patients with PPNs ≤20 mm, achieving a tool-in-lesion (TIL) rate of 99.4%.
- Diagnostic yield was 89.0%, with a sensitivity for malignancy of 91.5%, and a favorable safety profile with no pneumothorax reported.
- Median nodule size was 14.0 mm, with 54.8% located in the upper lobes and a median distance to the nearest pleural surface of 8.2 mm.
- The study suggests ssRAB with mCBCT offers diagnostic outcomes comparable to transthoracic biopsy but with improved safety.