Epidemiology and Clinical Characteristics of Fatty Pancreas Disease in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Systematic Review - PubMed
5 days ago
- #Metabolic Dysfunction
- #Epidemiology
- #Fatty Pancreas Disease
- Fatty pancreas disease (FPD) is characterized by excessive intrapancreatic fat deposition (IPFD) and is linked to metabolic dysfunction.
- A systematic review found the pooled prevalence of FPD in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) to be 54.32%, with significant heterogeneity.
- FPD prevalence was lower in Asian studies (35.59%) compared to non-Asian studies (75.05%).
- Patients with MASLD and FPD were older, had higher BMI, and were more likely to have diabetes, hypertension, and metabolic syndrome.
- The findings highlight the need for integrated, longitudinal studies to understand the prognostic and therapeutic relevance of IPFD in systemic metabolic dysfunction.