Epidemiology, ventilation, and outcomes of acute respiratory failure in immunocompromised patients from 103 intensive care units in 26 countries: a retrospective observational study - PubMed
3 hours ago
- #ICU outcomes
- #respiratory failure
- #immunocompromised
- Study focused on acute respiratory failure (ARF) in immunocompromised patients across 103 ICUs in 26 countries.
- Main causes of immunodeficiency were hematological (48.3%) and solid malignancies (38.7%).
- Infection was the leading cause of ARF (62.0%), with 53.7% having multiple contributing factors.
- 30-day mortality rate was 47.3%, with predictors including older age, higher comorbidity scores, and invasive fungal infections.
- Protective factors included solid organ transplants, higher PaO2/FiO2 ratios, and high-flow nasal oxygen therapy.
- Findings aim to improve clinical decisions and management for immunocompromised patients with ARF.