Trends of Carbapenem-Resistant Gram-negative Bacteria in China: A Surveillance Study Between 2015 and 2024 - PubMed
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- #Antimicrobial Resistance
- #Surveillance Study
- #Gram-negative Bacteria
- Surveillance study on carbapenem-resistant gram-negative bacteria in China from 2015 to 2024.
- 339,513 clinical isolates tested; carbapenem resistance in Enterobacterales generally below 13%, except Klebsiella spp. (20.4%-21.9%).
- High susceptibility to tigecycline, colistin, and polymyxin B in most Enterobacterales (resistance rates 0.1%-15.4%).
- Meropenem-resistant Pseudomonas aeruginosa detection rate decreased from 31.4% (2018) to 21.5% (2024).
- Meropenem-resistant Acinetobacter baumannii detection rate remained high (64.9% in 2015 to 68.3% in 2024).
- Multidrug-resistant bacteria pose significant challenges; calls for enhanced surveillance and rational antimicrobial use.