Headache prevalence and types in multiple sclerosis and related neuroimmunological diseases: A multicenter study - PubMed
6 hours ago
- #headache prevalence
- #neuroimmunological disorders
- #tension-type headache
- Headache prevalence in neuroimmunological disorders: 54.1% in multiple sclerosis (MS), 63.2% in neuromyelitis optica spectrum disorder (NMOSD), 43.1% in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), 43.3% in myasthenia gravis (MG), and 43.5% in healthy controls.
- MS and NMOSD groups had significantly higher odds of any headache compared to controls after correction, but no difference in migraine prevalence was observed across groups (MS 16.0%, NMOSD 16.0%, MOGAD 9.8%, MG 12.5%, controls 17.0%).
- Tension-type headache (TTH) was significantly higher in MS (24.0%) and NMOSD (37.7%) than in controls (16.7%) after adjusting for age and sex, with no association found between headache severity and disease activity or therapy in MS, NMOSD, or MOGAD.