Validated early detection metrics reduce the population requiring liver fibrosis screening - PubMed
5 hours ago
- #Screening
- #Risk stratification
- #Liver fibrosis
- Current guidelines identify 60-76% of adults for fibrosis screening, burdening healthcare.
- A refined screening strategy reduces the target population to 10-22% for screening.
- The refined criteria increase disease prevalence among screening-eligible individuals to 28%.
- Those not eligible maintain low risk (4% prevalence) of liver fibrosis.
- Validation across cohorts shows consistent results with higher cirrhosis and liver-related death risks in eligible groups.