Ferroptosis and Alzheimer's disease: a new insight into neurodegeneration - PubMed
2 months ago
- #Alzheimer's disease
- #Neurodegeneration
- #Ferroptosis
- Alzheimer's disease (AD) is a chronic neurodegenerative disorder affecting the aging population.
- Pathological hallmarks of AD include amyloid-β plaques and neurofibrillary tangles (NFTs).
- Ferroptosis, a form of regulated cell death, may contribute to AD pathogenesis.
- The review examines the amyloid cascade hypothesis and ferroptosis's role in AD.
- Current therapeutic strategies targeting ferroptosis inhibition in AD are discussed.
- Recent advances in understanding ferroptosis could guide future AD treatments.