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National trends in acute viral hepatitis in China from 1990-2023: An analysis of the Global Burden of Disease 2023 update - PubMed

14 hours ago
  • #viral hepatitis
  • #epidemiology
  • #China
  • Study analyzes national trends in acute viral hepatitis (AVH) in China from 1990 to 2023 using the Global Burden of Disease (GBD) 2023 dataset.
  • In 2023, China had an estimated 48.7 million AVH cases, including 19.0 million acute hepatitis A (AHA), 19.2 million acute hepatitis B (AHB), 1.35 million acute hepatitis C (AHC), and 9.2 million acute hepatitis E (AHE).
  • From 1990 to 2023, the overall age-standardized incidence rates (ASIR) of AVH in China declined (AAPC = -0.90%).
  • Divergent trends were observed in the past decade: AHC incidence increased (AAPC = 1.42%), AHE remained stable, while AHA and AHB decreased.
  • Age-standardized mortality and DALYs rates for AVH significantly decreased over the study period.
  • An upward trend in standardized incidence was noted among individuals aged 25-29 years (AAPC = 0.14%).
  • Projections indicate a continued decline in AVH incidence from 2024 to 2030.
  • Recommendations include strengthening AHB vaccination among younger populations and implementing targeted strategies for high-risk AHC groups.