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BRAHMA represses STOP1-NRT1.1 module to control plant rhizosphere alkalization and acid stress adaptation - PubMed

5 hours ago
  • #plant biology
  • #nitrogen uptake
  • #acid stress
  • BRAHMA (BRM) represses the STOP1-NRT1.1 module to control plant rhizosphere alkalization and acid stress adaptation.
  • Acidic soils cover 40-50% of the world's arable lands, severely restricting root development and nutrient acquisition.
  • The transcription factor STOP1 mitigates acid stress by activating H+/NO3- symport via NRT1.1, driving rhizosphere alkalinization.
  • BRM physically interacts with STOP1 and represses the STOP1-dependent activation of NRT1.1 expression under chronic acidity.
  • Low pH triggers BRM degradation, relieving repression on the STOP1-NRT1.1 pathway and enabling robust H+-coupled NO3- uptake.
  • The BRM-STOP1-NRT1.1 axis integrates NO3- acquisition with pH homeostasis, enhancing crop resilience to acid soils and improving nitrogen use efficiency (NUE).