Health impacts of micro- and nanoplastics in humans: systematic review of in vivo evidence - PubMed
6 hours ago
- #health impacts
- #microplastics
- #systematic review
- Systematic review examines health impacts of micro- and nanoplastics (MNPs) in humans.
- MNPs linked to oxidative stress, inflammation, and endocrine disruption in lab models.
- 25 studies included, detecting MNPs in cardiovascular, reproductive, gastrointestinal, respiratory, and ocular systems.
- Common polymers found: polyethylene, polypropylene, polyvinyl chloride, polyethylene terephthalate, and polystyrene.
- Cardiovascular studies show MNPs correlate with inflammatory markers and adverse cardiac events.
- Reproductive studies link MNPs to reduced sperm quality and accumulation in tumor and placental samples.
- Gastrointestinal studies associate fecal MNPs with liver enzyme elevations and gut dysbiosis.
- Respiratory and ocular studies detect MNPs in airway fluids and vitreous humor, linked to inflammation and increased intraocular pressure.
- Methodological heterogeneity and bias limit causal inference; prospective cohort studies needed.