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Vitamin D2 supplements can lead to a drop in Vitamin D3

20 hours ago
  • #supplements
  • #immune system
  • #vitamin D
  • Vitamin D2 supplements may reduce the body's concentration of vitamin D3, which is more easily used by the body.
  • Vitamin D3 is produced by the body when exposed to sunlight, while supplements can come from animal (D3) or plant (D2) sources.
  • A meta-analysis of 11 studies found that vitamin D2 supplementation leads to lower vitamin D3 levels, though the reason is unclear.
  • Vitamin D3 appears to have unique immune-supporting benefits, such as stimulating the type-I interferon signaling system.
  • Vitamin D3 supplements may be more beneficial for most people, but personal preferences (e.g., veganism) should be considered.
  • Older adults may benefit more from vitamin D2 due to reduced efficiency in converting D3 to its active form.
  • Plant-based vitamin D3 supplements are becoming more available, though further research is needed.
  • Vitamin D deficiency can lead to health issues like osteomalacia (rickets in children), causing fatigue, bone pain, and weakened immunity.
  • Experts emphasize the importance of vitamin D supplementation, especially in regions with limited sunlight.