Abdominal ultrasound activates afferent vagus nerve fibers and induces anti-inflammatory effects - PubMed
3 months ago
- #vagus-nerve
- #inflammation
- #ultrasound
- Abdominal ultrasound has anti-inflammatory effects by activating afferent vagus nerve fibers.
- The study used a murine model of LPS-induced endotoxemia to show reduced TNF-α levels with ultrasound.
- Anti-inflammatory effects were attenuated by subdiaphragmatic vagotomy or afferent vagal blockade.
- Electrophysiological recordings confirmed increased vagus nerve activity during ultrasound stimulation.
- Ultrasound induced c-Fos expression in the NTS, indicating central activation via vagal afferent input.
- The findings support the role of abdominal ultrasound in stimulating afferent vagal pathways to reduce inflammation.