Interventions for Migraine and Sleep: A Systematic Review Exploring Their Bidirectional Association - PubMed
5 hours ago
- #sleep-disorders
- #migraine
- #interventions
- Migraine and sleep disturbances have a bidirectional relationship, influencing each other's frequency and severity.
- Pharmacological treatments like erenumab, amitriptyline, propranolol, and onabotulinumtoxinA reduced migraine frequency and pain intensity, with variable effects on sleep quality.
- Melatonin showed no significant impact on migraine or sleep.
- Non-pharmacological treatments such as percutaneous electrical nerve stimulation, greater occipital nerve block, green light therapy, binaural beats, mindfulness, and dietary modifications improved both migraine symptoms and sleep.
- Digital Cognitive-Behavioral Therapy for Insomnia (CBT-I) significantly reduced headache days and improved sleep parameters, while standard CBT-I had mixed results.
- Study limitations include heterogeneity, small sample sizes, and variability in outcome measures, limiting generalizability.
- Integrated approaches combining migraine and sleep interventions show promise for symptom management.
- Further research is needed to refine treatment strategies and assess long-term effects.