Rapamycin Reduces Amyloid-β Plaques and Improves Behavioral Performance in a Sex-Dependent Manner in Mouse Models of Amyloidosis - PubMed
5 hours ago
- #Alzheimer's disease
- #rapamycin
- #microglia
- Rapamycin reduces amyloid-β plaques and improves behavioral performance in mouse models of amyloidosis.
- Effects of rapamycin are more pronounced in female mice.
- Rapamycin enhances microglial lysosomal degradation and promotes Aβ phagocytic clearance.
- The study highlights rapamycin's therapeutic potential in Alzheimer's disease treatment.