Intake of Fiber From Different Food Sources and Type 2 Diabetes Risk: An Integrated Analysis of Epidemiological and Multiomic Data - PubMed
4 hours ago
- #type-2-diabetes-risk
- #gut-microbiome
- #fiber-intake
- Higher total, cereal, and fruit fiber intakes are linked to reduced type 2 diabetes (T2D) risk, as shown in a study of 195,222 participants over up to 34 years.
- Total fiber (HR 0.88), cereal fiber (HR 0.77), and fruit fiber (HR 0.82) were associated with lower T2D risk, while vegetable fiber showed no significant association.
- Increased intake of total, cereal, and fruit fiber correlated with better plasma profiles for insulin, lipids, inflammation, and a metabolomic profile indicating lower T2D risk.
- Gut microbial species like Faecalibacterium prausnitzii and enzymes for butyric acid production were tied to higher fruit fiber intake and a lower T2D risk profile.
- The gut microbiome may mediate the beneficial effects of fruit fiber on T2D risk, suggesting a role in metabolic health through molecular pathways.