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Prognostic Effect of Sarcopenia and Nutritional Factors on Survival in Patients With Newly Diagnosed Multiple Myeloma: A Retrospective Exploratory Study - PubMed

5 hours ago
  • #nutritional assessment
  • #sarcopenia
  • #multiple myeloma
  • Sarcopenia was identified in 37.4% of 214 newly diagnosed multiple myeloma (NDMM) patients.
  • Patients with sarcopenia had shorter progression-free survival (PFS) and overall survival (OS).
  • Low prognostic nutritional index (PNI) and high controlling nutritional status (CONUT) scores were associated with worse PFS and OS.
  • A combined model of sarcopenia, PNI, and CONUT score strongly correlated with survival outcomes.
  • Sarcopenia was an independent predictor of shorter OS in multivariate analysis.