Association of muscle quality index with circadian syndrome: Evidence from NHANES - PubMed

4 hours ago

Muscle Quality Index (MQI) is a novel health metric calculated as the ratio of handgrip strength to skeletal muscle mass.
The study explores the association between MQI and circadian syndrome (CircS) using NHANES 2011-2014 data.
A cohort of 2250 American adults was analyzed, with 10.2% diagnosed with CircS.
Results show a significant negative linear association between MQI and CircS prevalence (OR = 0.35, 95% CI = 0.26, 0.46).
MQI also negatively correlates with components of CircS: elevated FPG, BP, WC, reduced HDL, and depression.
Subgroup analyses confirm the association is consistent across demographics and lifestyle factors.
ROC analysis indicates MQI (AUC = 0.713) is more reliable for identifying CircS than handgrip strength or skeletal muscle mass alone.
Promoting physical exercise, especially resistance training, may help reduce CircS risk.

Hasty Briefsbeta