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Dietary Quality and Microbiome Profiles among Rectal Cancer Patients: A Cross-Sectional Pilot Study - PubMed

7 hours ago
  • #Microbiome
  • #Rectal Cancer
  • #Dietary Quality
  • Examined gut microbial taxa abundances and predicted functional pathways in relation to dietary quality scores in rectal cancer patients post-neoadjuvant chemoradiotherapy.
  • Identified bacterial species from pantothenate and acetyl-coenzyme A biosynthesis pathways differing among dietary quality groups.
  • Found positive correlations between certain genera (Parvimonas, Caproiciproducens, uncultured Eggerthellaceae) and higher dietary quality scores.
  • Observed negative correlations between other genera (Prevotella, Rothia, Peptostreptococcus, etc.) and dietary quality scores.
  • Predicted pathways related to B-vitamin and enzyme cofactor biosynthesis were associated with higher dietary quality.
  • Higher abundances of species encoding vitamin B5-CoA biosynthesis pathways were noted in high-dietary-quality participants.