Dual-Pronged Lipid Nanocarriers Promote Immunotherapy for TNBC by Inducing Immunogenic Cell Death and Activating Lymphoid Immune Cells - PubMed
5 hours ago
- #Cancer Immunotherapy
- #TNBC
- #Nanocarriers
- The study proposes a dual-pronged lipid nanocarrier approach for immunotherapy in triple-negative breast cancer (TNBC).
- One component targets tumors to induce immunogenic cell death (ICD) and mature dendritic cells.
- The other targets lymph nodes to activate immune cells and enhance systemic antitumor immunity.
- Combination therapy shows improved inhibition of tumor growth and reduced metastasis in a mouse model.