CT-adipose measures identify severe SARS-CoV-2 risk beyond traditional obesity metrics: a C4R cohort study - PubMed
4 hours ago
- #Adipose Tissue
- #COVID-19
- #CT Imaging
- Higher BMI increases risk of respiratory failure and death from SARS-CoV-2 infection, but BMI is imprecise and does not account for adipose tissue distribution.
- CT-measured pericardial adipose tissue (PAT) and abdominal visceral adipose tissue (VAT) were associated with increased hazards of hospitalization or death from SARS-CoV-2, independent of BMI and clinical cardiometabolic comorbidities.
- Subcutaneous adipose tissue (SAT) was associated with hospitalization or death but not after adjustment for BMI and obesity complications.
- Hepatic adipose deposition was not associated with hospitalization or death.
- The study suggests that CT adipose measures can identify severe SARS-CoV-2 risk beyond traditional obesity metrics.