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Paranasal Sinus Squamous Cell Carcinoma and Adenocarcinoma: A SEER Database Analysis - PubMed

5 hours ago
  • #paranasal sinus tumors
  • #adenocarcinoma
  • #squamous cell carcinoma
  • Paranasal sinus tumors are rare and aggressive with poor outcomes.
  • Study analyzed SEER data (2000-2019) for squamous cell carcinoma (SCC) and adenocarcinoma (AC).
  • 5,276 SCC and 5,222 AC patients included; AC patients were younger with more advanced tumors.
  • Median overall survival (OS) for SCC was 203 months vs. 56 months for AC.
  • Key predictors for SCC survival: stage, primary site, and treatment.
  • Key predictors for AC survival: stage and treatment.
  • Combined surgery and radiation improved survival for both SCC and AC compared to radiation alone.
  • Nasal SCC had better survival than other sites.
  • Both SCC and AC of paranasal sinus have poor prognosis.