Clinical Criteria for the Definition of Refractory Septic Shock: A Joint Delphi Consensus from the Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) - Pu
6 hours ago
- #septic shock
- #Delphi consensus
- #critical care
- A joint Delphi consensus was conducted by SCCM and ESICM to define refractory septic shock.
- Refractory septic shock criteria include organ dysfunction markers, tissue perfusion indicators (lactate, capillary refill time), and fluid-responsiveness assessment.
- Vasoactive drugs at norepinephrine equivalents >0.5 µg/kg/min and critical care ultrasound (CCUS) use were agreed upon as diagnostic criteria.
- Consensus was reached on 13 clinical criteria out of 29 proposed statements after a five-round Delphi process.
- Refractory septic shock is characterized by persistent lactate elevation, prolonged capillary refill time, fluid unresponsiveness, and high vasopressor requirements.