Burden and Risk Factor Patterns of Reproductive System Tumors and Non-Tumor Diseases Among Asian Women, 1990-2021: Evidence from the GBD Study - PubMed
2 days ago
- #reproductive diseases
- #GBD study
- #women's health
- Female reproductive system diseases, including malignant tumors (breast, ovarian, uterine cancers) and non-neoplastic disorders (uterine fibroids, endometriosis, PCOS, infertility, PMS), pose major health challenges in Asia.
- The study analyzed data from the Global Burden of Disease (GBD) 2021 across 47 Asian countries (1990-2021), measuring incidence, prevalence, mortality, DALYs, and age-standardized rates.
- In 2021, these diseases accounted for over 33 million DALYs and ~600,000 deaths in Asia. Breast and cervical cancers were leading causes of mortality, while PMS and infertility heavily impacted younger women.
- From 1990-2021, case numbers rose due to population growth/aging, but age-standardized rates mostly declined (e.g., cervical cancer). PCOS and infertility showed the fastest increases.
- Key risk factors: high BMI/elevated glucose linked to breast/uterine cancers; smoking strongly associated with cervical cancer burden.
- The burden varies across Asia—malignant cancers dominate mortality/DALYs, but non-malignant disorders (e.g., infertility) increasingly affect younger women’s reproductive health.
- Tailored prevention strategies addressing SDI levels and modifiable risk factors are needed to reduce regional disparities.