European Society for Paediatric Gastroenterology, Hepatology and Nutrition/North American Society for Pediatric Gastroenterology, Hepatology and Nutrition guidelines for treatment of functional consti
4 hours ago
- #treatment guidelines
- #pediatric gastroenterology
- #functional constipation
- Guidelines for functional constipation (FC) treatment in children (0-18 years) were jointly developed by ESPGHAN and NASPGHAN using the GRADE approach.
- The guidelines include 11 evidence-based recommendations, 19 good practice statements, and a treatment algorithm, aiming for worldwide applicability.
- A systematic review of 102 RCTs identified major evidence gaps, highlighting the need for large pediatric RCTs on current treatments.
- Recommendations were based on consensus voting and a Delphi process to set thresholds for efficacy and safety outcomes.