Next generation sequencing approaches for the detection and characterization of enteroviruses in clinical, public health, and research settings: Expert view of the European non-polio enterovirus netwo
9 hours ago
- #Enteroviruses
- #Next-Generation Sequencing
- #Viral Genomics
- Next-Generation Sequencing (NGS) offers comprehensive full-genome analysis for enterovirus detection and characterization, surpassing current molecular methods like PCR and partial VP1 sequencing.
- Implementation of NGS faces challenges in standardizing wet-lab (laboratory workflows) and dry-lab (bioinformatics analyses) practices, which are not widely accessible in many laboratories.
- The European non-polio enterovirus network (ENPEN) provides expert recommendations to harmonize NGS use in clinical, public health, and research settings for improved virus management and epidemiological surveillance.