Quantifying Weight Loss Prior to Pancreatic Cancer Diagnosis: A Systematic Review and Meta-Analysis - PubMed
4 hours ago
- #pancreatic cancer
- #meta-analysis
- #weight loss
- The meta-analysis found that on average, participants with pancreatic cancer lost 5.9 kg of body weight prior to diagnosis.
- The average BMI change was -2.5 kg/m², indicating significant weight loss relative to body size.
- High heterogeneity between studies was observed (I² = 99.2% for weight loss and 82.6% for BMI change).
- Factors like diabetes status, weight loss timing, self-reporting, and publication year partially explained heterogeneity in weight loss.
- For BMI change, heterogeneity was influenced by cancer type, self-reporting, and publication year.
- The analysis included 25 studies with 25,971 participants, providing a reference for expected weight loss in pancreatic cancer to aid early detection.