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Scientists found a protein that drives brain aging – and how to stop it

8 hours ago
  • #brain aging
  • #FTL1 protein
  • #cognitive decline
  • Scientists identified a protein named FTL1 as a key driver of brain aging in mice.
  • Higher FTL1 levels in older mice correlated with fewer neural connections and memory decline.
  • Boosting FTL1 in young mice induced aging-like brain changes and simplified neuron structures.
  • Reducing FTL1 in older mice reversed impairments, restoring neural connections and memory performance.
  • FTL1 affects cellular metabolism in the hippocampus; metabolic-boosting compounds counteracted its negative effects.
  • The findings offer potential for therapies targeting FTL1 to mitigate age-related cognitive decline.